The year's best serums include this tried-and-true option from Saint Jane.
As a longtime beauty writer and editor who's lucky enough to have the best face serums stocked in her bathroom cabinet, it might be surprisingly to learn that I went many, many years without regularly using one. I'll admit that before I was enlightened, I thought a good moisturizer was all it took to have healthy, hydrated skin. But sometimes you actually do need a little extra support in the skin care department and you may find that serums are a total game changer for any anti-aging regimen.
Serums hold a universe of beneficial anti-aging ingredients in their little bottles, including those that help fight blemishes and wrinkles, improve rough texture, firm skin, lighten dark spots and brighten dull complexions. The best serums are made with high concentrations of high-quality, effective ingredients, which means they often come with a high price tag.
The trick to finding the best facial serum for you is to identify which skin concerns you want to treat — dryness, dullness, fine lines or discoloration (pro tip: The best hyaluronic acid serums are always a good place to start for anyone, regardless of skin type). With an array of brands promising big results, the choice can be overwhelming, especially when you're trying to find one that fits your budget or makes a worth-it Friday paycheck splurge.
Below, you'll find the top serums I've found, from my favorite vitamin C serum to the best luxury pick along with expert tips on what you should look for in a serum depending on your skin type and how to incorporate these products into your skin care routine long-term.
Update, August 25, 2025: We checked all product prices and availability. Our No. 1 pick for the best face serum remains unchanged.
Formulation: Gel | Size: 1.5 ounces | Skin types: Normal, dry, combination, oily | Key ingredients: Niacinamide, hyaluronic acid, star flower, sacred lotus
Of all the serums I've ever used, Saint Jane's Star Flower remains on my favorites list. So much so that whenever I see the bottle, I can't help but pump out a couple of drops and apply it right then and there. Micro pearls, which house all of the active ingredients, burst when you apply them to your skin, and it is like heaven.
Not only is the formula deliciously hydrating, but it makes the pores on my nose and cheeks look smaller. For that reason, I love using this in the morning before sunscreen and makeup. The star flower not only sounds pretty, but it helps with redness, while the sacred lotus helps diminish pores. My skin always looks more even when I use it regularly.
Formulation: Gel | Size: 1.69 ounces | Skin types: All, especially dry and sensitive | Key ingredients: Vichy's Volcanic Water and hyaluronic acid
This drugstore favorite is suitable for all skin types, but mostly for those with dry, dehydrated skin. It was clinically tested by over 300 dermatologists who studied its effectiveness on 3,200 women. The results were impressive: 8 out of 10 women reported that their skin felt smoother immediately, then plumped and toned after one week, and more luminous after a month.
The ingredients are pretty simple, at least compared with other serums on this list. It contains Vichy's special Volcanic Water, which is sourced from French volcanoes and contains 15 essential minerals that strengthen, protect and repair the skin barrier.
Formulation: Cream | Size: 1 ounce | Skin types: All | Key ingredients: 20% L-ascorbic acid, squalane, green tea actives, tartaric acid
The beauty industry has made great strides in vitamin C technology, and there isn't a better example than Universal C Skin Refiner from BeautyStat, the skin care brand founded by renowned cosmetic chemist Ron Robinson. This award-winning serum contains 20% pure vitamin C, and it doesn't oxidize or turn brown (I'm still traumatized from the vitamin C's of my past).
It has a slight tingling sensation, so I started low and slow with this, but then used it twice a day and saw a difference in my skin's texture in just a few days. After a month, you should start to see an improvement in fine lines and wrinkles. If you're looking for a new vitamin C serum, don't skip out on this one!
Formulation: Cream | Size: 0.5 ounce | Skin types: Normal, combination, oily, mature | Key ingredients: Vitamin C, niacinamide, squalane, white tea, pomegranate
Splurging on a skin care product should always be worth it. It has to work, of course, but for me, it should also be made with high-grade, efficacious ingredients that are sustainably sourced and packaged mindfully. (A co-sign from Zoë Kravitz and Tracee Ellis Ross never hurts either.)
I'm obsessed with Retrouvé’s entire skin care line, but this lightweight serum stands out. It's particularly nice for boosting a dull complexion — it makes my skin look brighter instantly — and I love the light, natural fragrance. The family-owned brand (founded by Kiehl's heiress Jami Morse Heidegger and her husband, Klaus Heidegger) also uses ingredients harvested directly from the family farm in Malibu, Calif., which sounds like a dream, honestly.
Formulation: Cream/gel | Size: 1 ounce | Skin types: All | Key ingredients: Growth factors, peptides, marine extract, French flax seed
SkinMedica's TNS Advanced+ Serum is known as a holy grail product for aging skin. It's been a game changer in my routine ever since I turned 40. It has a dual chamber that simultaneously dispenses two formulas that blend to support collagen and elastin levels in the skin. The first chamber has the TNS-MR formula, which contains a growth factor blend for healthy skin function and nourishing peptides, while the second chamber contains marine extract, microalgae and French flax seed for supporting skin renewal and repairing skin functions.
This serum is easy to use compared with other products that promise the same benefits (I didn't experience any stinging, like with actives). I used it twice a day and noticed my acne scars getting lighter and rough texture improving after a couple of weeks.
This is far from the most potent product on our list, but it still has skin-nourishing merits. If you're in the market for a moderately priced serum that addresses signs of aging and uses only natural ingredients, this one is for you. Polyglutamic acid, ceramides, quinoa extract and silver ear mushroom aim to improve wrinkles and reduce the appearance of sagging skin and large pores.
Glow Recipe's fruit-infused serums are always on my favorites list, but the Strawberry BHA Pore-Smooth Blur Drops impressed me on the first try. A few drops of the serum were dispensed from its cute, travel-friendly packaging and my pores were instantly blurred (without silicone!). It doesn't really provide hydration, which is why it doesn't make our main list — it's not a substitute for my go-to day serum/primer. Still, I can see myself packing this cutie for all my travels.
Formulation: Gel | Size: 1.69 ounces | Skin types: All, especially dry and sensitive | Key ingredients: Vichy's Volcanic Water and hyaluronic acid
This drugstore favorite is suitable for all skin types, but mostly for those with dry, dehydrated skin. It was clinically tested by over 300 dermatologists who studied its effectiveness on 3,200 women. The results were impressive: 8 out of 10 women reported that their skin felt smoother immediately, then plumped and toned after one week, and more luminous after a month.
The ingredients are pretty simple, at least compared with other serums on this list. It contains Vichy's special Volcanic Water, which is sourced from French volcanoes and contains 15 essential minerals that strengthen, protect and repair the skin barrier.
Formulation: Cream | Size: 1 ounce | Skin types: All | Key ingredients: 20% L-ascorbic acid, squalane, green tea actives, tartaric acid
The beauty industry has made great strides in vitamin C serums, and there isn't a better example than Universal C Skin Refiner from BeautyStat, the skin care brand founded by renowned cosmetic chemist Ron Robinson. This award-winning serum contains 20% pure vitamin C, and it doesn't oxidize or turn brown (I'm still traumatized from the vitamin C's of my past).
It has a slight tingling sensation, so I started low and slow with this, but then used it twice a day and saw a difference in my skin's texture in just a few days. After a month, you should start to see an improvement in fine lines and wrinkles. If you're looking for a new vitamin C serum, don't skip out on this one!
Formulation: Cream | Size: 0.5 ounce | Skin types: Normal, combination, oily, mature | Key ingredients: Vitamin C, niacinamide, squalane, white tea, pomegranate
Splurging on a skin care product should always be worth it. It has to work, of course, but for me, it should also be made with high-grade, efficacious ingredients that are sustainably sourced and packaged mindfully. (A co-sign from Zoë Kravitz and Tracee Ellis Ross never hurts either.)
I'm obsessed with Retrouvé’s entire skin care line, but this lightweight serum stands out. It's particularly nice for boosting a dull complexion — it makes my skin look brighter instantly — and I love the light, natural fragrance. The family-owned brand (founded by Kiehl's heiress Jami Morse Heidegger and her husband, Klaus Heidegger) also uses ingredients harvested directly from the family farm in Malibu, Calif., which sounds like a dream, honestly.
I’ve been covering beauty for more than a decade, and like many women over 40, my skin has changed (thanks a lot, disappearing collagen). While yes, I always dream of a quick miracle, I have priorities when looking for a good serum to address my various concerns. For me, a face serum is the workhorse of a routine: it’s the concentrated step that can deliver visible results when chosen wisely, so the final step, i.e., moisturizer, can relax and do its job.
For this story, I put my face to work, testing dozens upon dozens of face serums and sorting them by cost, effectiveness, ingredients and benefits. I noted which ones made my skin feel moisturized, improved its texture and generally made me look like a glowing angel baby — because that's the goal, right? I happily slathered them on and evaluated them on the following:
Hydration: Did the serum noticeably plump and smooth my skin, or did it leave me feeling tight and dry?
Texture: Was it lightweight and easy to layer, or did it pill under moisturizer and sunscreen?
Ingredients: Did the formula contain proven skin care players for my mature skin — like vitamin C, peptides, hyaluronic acid or retinol?
Absorption: Did the serum sink in quickly without leaving a sticky residue or did it sit on top of the skin?
Results: After several weeks, did I notice improvements in brightness, firmness, hydration or fine lines?
Compatibility: How well did each serum work with the rest of my routine, like moisturizer, SPF and makeup?
Mature-skin friendliness: Above all, I judged how supportive each formula was for over-40 skin. Did it enhance radiance, hydration and smoothness, or did it highlight sensitivity, dryness or texture issues?
So many serums, so little face. There were a few strong contenders for our best serums list, but ultimately, for a variety of reasons, I had to leave these out.
Mad Hippie Corrective Peptide Serum: If you're in the market for a moderately priced serum that addresses signs of aging and uses only natural ingredients, this is a fairly decent choice, but I wanted something a little more potent for anti-aging concerns.
Glow Recipe Strawberry BHA Pore-Smooth Blur Drops: While these drops were good for blurring pores (sans silicone, if you prefer to avoid it), they didn't really provide hydration, which is why it doesn't make our main list — it's not a substitute for my go-to day serum/primer.
SkinCeuticals C E Ferulic: This cult-favorite has some seriously potent anti-aging ingredients, like but is also controversial due to its high price tag, notoriously unstable formula and funky scent.
Good Genes All-In-One Lactic Acid Treatment Serum: This lactic acid-centered serum is another popular choice, but it feels way too spicy on my skin these days. It helps with texture and brightening concerns, but there are better alternatives that won't aggravate my skin.
As we age, our collagen declines, resulting in our skin naturally losing moisture and plumpness. A good serum should deliver lightweight yet deep hydration. Look for ones that have hyaluronic acid (like our Saint Jane picky) or glycerin to draw water into the skin and keep it looking supple without feeling sticky. Layering a serum like this under your moisturizer can make a noticeable difference in fine lines.
Not all serums are created equal, and that’s a good thing. If dullness is your main concern, look for brighteners like vitamin C, which is a key ingredient in our Retrouvé winner. For firmness, peptides and growth factors are key. If texture or fine lines are top of mind, retinol (or gentler bakuchiol) is worth exploring. Think of serums as your “treatment step” — choose the one that speaks directly to your skin’s needs.
A serum should feel like it disappears into your skin, not sit on top or ball up under makeup. For mature skin, opt for a formula that sinks in quickly but still leaves your skin feeling cushioned, not tight. Water-based serums, like the Vichy one we love, are great for hydration, while silky, slightly oily textures can suit drier skin.
With serums, it’s not just about the ingredients; it’s also about how much of it is in them! Look for clinically proven concentrations, like our Beautystat pick, which contains 20% vitamin C. And don’t forget antioxidants, like vitamin E, resveratrol or green tea, which help defend against environmental damage that accelerates aging.
Just like sunscreen, the best serum is the one you’ll actually use consistently. Make sure it layers well under your moisturizer and sunscreen without pilling. If you’re already using strong actives (like retinoids or exfoliating acids), choose a serum that complements rather than competes,. Soothing formulas with niacinamide or ceramides are a great choice.
Of course, it all boils down to results! A great serum should give you both instant gratification (hydrated, glowing skin right after applying) and longer-term benefits (firmer, smoother, more even skin over weeks). The best ones do both, so you see and feel why it’s worth the extra (usually easy) step.
Face serums are a vital step in many a skin care routine. But the old me (who didn't use face serums) thought a simple moisturizer was fine. According to Dr. Angela Lamb, a board-certified dermatologist based in New York City, face serums are lightweight products that contain high concentrations of active ingredients targeting specific skin concerns. "Benefits of a face serum include delivering potent ingredients deeper into the skin, addressing specific concerns such as fine lines, wrinkles, dullness or hyperpigmentation, and providing hydration and nourishment," she says. If only I had understood this sooner.
If you usually apply a face serum as the second or third step in your routine, you're doing it right. (It's my second step if I'm feeling a little lazy, but if I use an essence, it ends up being my third.) "You can apply a face serum after cleansing and toning your skin, but before applying moisturizer," Lamb says. "This allows the active ingredients in the serum to penetrate the skin more effectively."
As we've learned, not all skin care products are equal, and some ingredients are better suited for certain skin types than others. When it comes to dry skin, Lamb says to look for face serums that contain hyaluronic acid, vitamin E, argan oil or rosehip oil. For oily skin, she says "lightweight serums with ingredients like niacinamide or salicylic acid to control oil production and minimize pores" are your best bet.
Fragrance-free, hypoallergenic formulas are best for sensitive skin types. As for mature skin, Lamb says "serums containing retinol, peptides or antioxidants like vitamin C to target signs of aging" are most beneficial.
I switch face serums depending on the time of day. For example, I’ll use a vitamin C serum in the morning, and a more hydrating serum, or one with acids, at night. But it's not a hard-and-fast rule. "You don't necessarily need to use a different face serum for a.m. and p.m., but some serums may contain ingredients like retinol that are best used at night due to increased sensitivity to sunlight," Lamb says.
Angela Lamb, MD, board-certified dermatologist and director of Westside Mount Sinai Dermatology in New York City
We received complimentary samples of some products and purchased others ourselves, but we reviewed all products using the same objective criteria.
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